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Contributions of DNA Damage to Alzheimer’s Disease
Alzheimer’s disease (AD) is the most common type of neurodegenerative disease. Its typical pathology consists of extracellular amyloid-β (Aβ) plaques and intracellular tau neurofibrillary tangles. Mutations in the APP, PSEN1, and PSEN2 genes increase Aβ production and aggregation, and thus cause ear...
Autores principales: | Lin, Xiaozeng, Kapoor, Anil, Gu, Yan, Chow, Mathilda Jing, Peng, Jingyi, Zhao, Kuncheng, Tang, Damu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084447/ https://www.ncbi.nlm.nih.gov/pubmed/32121304 http://dx.doi.org/10.3390/ijms21051666 |
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