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Homoarginine- and Creatine-Dependent Gene Regulation in Murine Brains with l-Arginine:Glycine Amidinotransferase Deficiency

l-arginine:glycine amidinotransferase (AGAT) and its metabolites homoarginine (hArg) and creatine have been linked to stroke pathology in both human and mouse studies. However, a comprehensive understanding of the underlying molecular mechanism is lacking. To investigate transcriptional changes in c...

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Detalles Bibliográficos
Autores principales: Jensen, Märit, Müller, Christian, Schwedhelm, Edzard, Arunachalam, Priyadharshini, Gelderblom, Mathias, Magnus, Tim, Gerloff, Christian, Zeller, Tanja, Choe, Chi-un
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084559/
https://www.ncbi.nlm.nih.gov/pubmed/32182846
http://dx.doi.org/10.3390/ijms21051865