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Alternatively Constructed Estrogen Receptor Alpha-Driven Super-Enhancers Result in Similar Gene Expression in Breast and Endometrial Cell Lines

Super-enhancers (SEs) are clusters of highly active enhancers, regulating cell type-specific and disease-related genes, including oncogenes. The individual regulatory regions within SEs might be simultaneously bound by different transcription factors (TFs) and co-regulators, which together establish...

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Detalles Bibliográficos
Autores principales: Bojcsuk, Dóra, Nagy, Gergely, Bálint, Bálint László
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084573/
https://www.ncbi.nlm.nih.gov/pubmed/32120995
http://dx.doi.org/10.3390/ijms21051630