In Vivo Allergen-Activated Eosinophils Promote Collagen I and Fibronectin Gene Expression in Airway Smooth Muscle Cells via TGF-β1 Signaling Pathway in Asthma

Eosinophils infiltration and releasing TGF-β1 in the airways has been implicated in the pathogenesis of asthma, especially during acute episodes provoked by an allergen. TGF-β1 is a major mediator involved in pro-inflammatory responses and fibrotic tissue remodeling in asthma. We aimed to evaluate t...

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Detalles Bibliográficos
Autores principales: Janulaityte, Ieva, Januskevicius, Andrius, Kalinauskaite-Zukauske, Virginija, Bajoriuniene, Ieva, Malakauskas, Kestutis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084581/
https://www.ncbi.nlm.nih.gov/pubmed/32155894
http://dx.doi.org/10.3390/ijms21051837

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084581/
https://www.ncbi.nlm.nih.gov/pubmed/32155894
http://dx.doi.org/10.3390/ijms21051837

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