Molecular Interactions of the Polysialytransferase Domain (PSTD) in ST8Sia IV with CMP-Sialic Acid and Polysialic Acid Required for Polysialylation of the Neural Cell Adhesion Molecule Proteins: An NMR Study

Polysialic acid (polySia) is an unusual glycan that posttranslational modifies neural cell adhesion molecule (NCAM) proteins in mammalian cells. The up-regulated expression of polySia-NCAM is associated with tumor progression in many metastatic human cancers and in neurocognitive processes. Two memb...

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Detalles Bibliográficos
Autores principales: Liao, Si-Ming, Lu, Bo, Liu, Xue-Hui, Lu, Zhi-Long, Liang, Shi-Jie, Chen, Dong, Troy, Frederic A., Huang, Ri-Bo, Zhou, Guo-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084582/
https://www.ncbi.nlm.nih.gov/pubmed/32111064
http://dx.doi.org/10.3390/ijms21051590

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084582/
https://www.ncbi.nlm.nih.gov/pubmed/32111064
http://dx.doi.org/10.3390/ijms21051590

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