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Design, Synthesis, and Biological Evaluation of Two Series of Novel A-Ring Fused Steroidal Pyrazines as Potential Anticancer Agents

Background: Increasingly, different heterocyclic systems have been introduced into the steroid nucleus to significantly enhance the antitumor activities of steroid molecules. However, in this study, few literature precedents describing the pyrazine heterocyclic-condensed modification to an A-ring of...

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Detalles Bibliográficos
Autores principales: Wang, Shijun, Yuan, Xiaorong, Qian, Hao, Li, Na, Wang, Junru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084598/
https://www.ncbi.nlm.nih.gov/pubmed/32121303
http://dx.doi.org/10.3390/ijms21051665