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Design, Synthesis, and Biological Evaluation of Two Series of Novel A-Ring Fused Steroidal Pyrazines as Potential Anticancer Agents
Background: Increasingly, different heterocyclic systems have been introduced into the steroid nucleus to significantly enhance the antitumor activities of steroid molecules. However, in this study, few literature precedents describing the pyrazine heterocyclic-condensed modification to an A-ring of...
Autores principales: | Wang, Shijun, Yuan, Xiaorong, Qian, Hao, Li, Na, Wang, Junru |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084598/ https://www.ncbi.nlm.nih.gov/pubmed/32121303 http://dx.doi.org/10.3390/ijms21051665 |
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