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Abnormal Lysosomal Positioning and Small Extracellular Vesicle Secretion in Arterial Stiffening and Calcification of Mice Lacking Mucolipin 1 Gene

Recent studies have shown that arterial medial calcification is mediated by abnormal release of exosomes/small extracellular vesicles from vascular smooth muscle cells (VSMCs) and that small extracellular vesicle (sEV) secretion from cells is associated with lysosome activity. The present study was...

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Detalles Bibliográficos
Autores principales: Bhat, Owais M., Yuan, Xinxu, Camus, Sarah, Salloum, Fadi N., Li, Pin-Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084670/
https://www.ncbi.nlm.nih.gov/pubmed/32138242
http://dx.doi.org/10.3390/ijms21051713