N-terminal Backbone Pairing Shifts in CCL5-(12)AAA(14) Dimer Interface: Structural Significance of the FAY Sequence

CC-type chemokine ligand 5 (CCL5) has been known to regulate immune responses by mediating the chemotaxis of leukocytes. Depending on the environment, CCL5 forms different orders of oligomers to interact with targets and create functional diversity. A recent CCL5 trimer structure revealed that the N...

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Detalles Bibliográficos
Autores principales: Li, Jin-Ye, Chen, Yi-Chen, Lee, Yi-Zong, Huang, Chun-Hsiang, Sue, Shih-Che
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084690/
https://www.ncbi.nlm.nih.gov/pubmed/32121575
http://dx.doi.org/10.3390/ijms21051689

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084690/
https://www.ncbi.nlm.nih.gov/pubmed/32121575
http://dx.doi.org/10.3390/ijms21051689

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