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N-terminal Backbone Pairing Shifts in CCL5-(12)AAA(14) Dimer Interface: Structural Significance of the FAY Sequence
CC-type chemokine ligand 5 (CCL5) has been known to regulate immune responses by mediating the chemotaxis of leukocytes. Depending on the environment, CCL5 forms different orders of oligomers to interact with targets and create functional diversity. A recent CCL5 trimer structure revealed that the N...
Autores principales: | Li, Jin-Ye, Chen, Yi-Chen, Lee, Yi-Zong, Huang, Chun-Hsiang, Sue, Shih-Che |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084690/ https://www.ncbi.nlm.nih.gov/pubmed/32121575 http://dx.doi.org/10.3390/ijms21051689 |
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