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DROSHA-Dependent miRNA and AIM2 Inflammasome Activation in Idiopathic Pulmonary Fibrosis

Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive interstitial lung disease. Chronic lung inflammation is linked to the pathogenesis of IPF. DROSHA, a class 2 ribonuclease III enzyme, has an important role in the biogenesis of microRNA (miRNA). The function of miRNAs has been identified...

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Detalles Bibliográficos
Autores principales: Cho, Soo Jung, Lee, Mihye, Stout-Delgado, Heather W., Moon, Jong-Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084700/
https://www.ncbi.nlm.nih.gov/pubmed/32121297
http://dx.doi.org/10.3390/ijms21051668