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Synergistic Upregulation of Target Genes by TET1 and VP64 in the dCas9–SunTag Platform

Overexpression of a gene of interest is a general approach used in both basic research and therapeutic applications. However, the conventional approach involving overexpression of exogenous genes has difficulty achieving complete genome coverage, and is also limited by the cloning capacity of viral...

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Detalles Bibliográficos
Autores principales: Morita, Sumiyo, Horii, Takuro, Kimura, Mika, Hatada, Izuho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084704/
https://www.ncbi.nlm.nih.gov/pubmed/32106616
http://dx.doi.org/10.3390/ijms21051574