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Synergistic Upregulation of Target Genes by TET1 and VP64 in the dCas9–SunTag Platform
Overexpression of a gene of interest is a general approach used in both basic research and therapeutic applications. However, the conventional approach involving overexpression of exogenous genes has difficulty achieving complete genome coverage, and is also limited by the cloning capacity of viral...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084704/ https://www.ncbi.nlm.nih.gov/pubmed/32106616 http://dx.doi.org/10.3390/ijms21051574 |