Perinuclear Lamin A and Nucleoplasmic Lamin B2 Characterize Two Types of Hippocampal Neurons through Alzheimer’s Disease Progression

Background. Recent reports point to a nuclear origin of Alzheimer’s disease (AD). Aged postmitotic neurons try to repair their damaged DNA by entering the cell cycle. This aberrant cell cycle re-entry involves chromatin modifications where nuclear Tau and the nuclear lamin are involved. The purpose...

Descripción completa

Detalles Bibliográficos
Autores principales: Gil, Laura, Niño, Sandra A., Chi-Ahumada, Erika, Rodríguez-Leyva, Ildelfonso, Guerrero, Carmen, Rebolledo, Ana Belén, Arias, José A., Jiménez-Capdeville, María E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084765/
https://www.ncbi.nlm.nih.gov/pubmed/32155994
http://dx.doi.org/10.3390/ijms21051841

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084765/
https://www.ncbi.nlm.nih.gov/pubmed/32155994
http://dx.doi.org/10.3390/ijms21051841

Ejemplares similares