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Erythropoietin-Induced Changes in Bone and Bone Marrow in Mouse Models of Diet-Induced Obesity

Obesity remodels bone and increases bone marrow adipocytes (BMAT), which negatively regulate hematopoiesis and bone. Reduced BMAT could restore altered hematopoiesis and bone features. We analyzed the potential of erythropoietin (EPO), the cytokine required for erythropoiesis, to inhibit BMAT in C57...

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Detalles Bibliográficos
Autores principales: Suresh, Sukanya, Alvarez, Josue Caban, Dey, Soumyadeep, Noguchi, Constance Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084787/
https://www.ncbi.nlm.nih.gov/pubmed/32121294
http://dx.doi.org/10.3390/ijms21051657