Variability in HIV-1 Integrase Gene and 3′-Polypurine Tract Sequences in Cameroon Clinical Isolates, and Implications for Integrase Inhibitors Efficacy

Integrase strand-transfer inhibitors (INSTIs) are now included in preferred first-line antiretroviral therapy (ART) for HIV-infected adults. Studies of Western clade-B HIV-1 show increased resistance to INSTIs following mutations in integrase and nef 3′polypurine tract (3′-PPT). With anticipated shi...

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Detalles Bibliográficos
Autores principales: Acharya, Arpan, Tagny, Claude T., Mbanya, Dora, Fonsah, Julius Y., Nchindap, Emilienne, Kenmogne, Léopoldine, Jihyun, Ma, Njamnshi, Alfred K., Kanmogne, Georgette D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084836/
https://www.ncbi.nlm.nih.gov/pubmed/32106437
http://dx.doi.org/10.3390/ijms21051553

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084836/
https://www.ncbi.nlm.nih.gov/pubmed/32106437
http://dx.doi.org/10.3390/ijms21051553

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