Leucine-Rich Repeat Kinase 2 Controls Inflammatory Cytokines Production through NF-κB Phosphorylation and Antigen Presentation in Bone Marrow-Derived Dendritic Cells

Leucine-rich repeat kinase 2 (LRRK2) is the causal molecule of familial Parkinson’s disease. Although the characteristics of LRRK2 have gradually been revealed, its true physiological functions remain unknown. LRRK2 is highly expressed in immune cells such as B2 cells and macrophages, suggesting tha...

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Detalles Bibliográficos
Autores principales: Kubo, Makoto, Nagashima, Ryuichi, Kurihara, Mitsue, Kawakami, Fumitaka, Maekawa, Tatsunori, Eshima, Koji, Ohta, Etsuro, Kato, Hirotomo, Obata, Fumiya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084871/
https://www.ncbi.nlm.nih.gov/pubmed/32164260
http://dx.doi.org/10.3390/ijms21051890

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084871/
https://www.ncbi.nlm.nih.gov/pubmed/32164260
http://dx.doi.org/10.3390/ijms21051890

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