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Abrogation of IFN-γ Signaling May not Worsen Sensitivity to PD-1/PD-L1 Blockade

Programmed cell death protein 1 (PD-1)/PD-1 ligand 1 (PD-L1) blockade is a promising therapy for various cancer types, but most patients are still resistant. Therefore, a larger number of predictive biomarkers is necessary. In this study, we assessed whether a loss-of-function mutation of the interf...

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Detalles Bibliográficos
Autores principales: Vackova, Julie, Piatakova, Adrianna, Polakova, Ingrid, Smahel, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084912/
https://www.ncbi.nlm.nih.gov/pubmed/32155707
http://dx.doi.org/10.3390/ijms21051806