Adenine inhibits growth of hepatocellular carcinoma cells via AMPK-mediated S phase arrest and apoptotic cascade

Background: Adenine exhibits potential anticancer activity against several types of malignancies. However, whether adenine has anticancer effects on hepatocellular carcinoma (HCC) cells is incompletely explored. Methods: Human HCC cell lines HepG2 and SK-Hep-1 (p53-wild type) and Hep3B (p53-deficien...

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Detalles Bibliográficos
Autores principales: Su, Wei-Wen, Huang, Jen-Yu, Chen, Han-Min, Lin, Jiun-Tsai, Kao, Shao-Hsuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7085215/
https://www.ncbi.nlm.nih.gov/pubmed/32210718
http://dx.doi.org/10.7150/ijms.42086

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7085215/
https://www.ncbi.nlm.nih.gov/pubmed/32210718
http://dx.doi.org/10.7150/ijms.42086

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