Quantitative determination of niraparib and olaparib tumor distribution by mass spectrometry imaging

Rationale: Optimal intratumor distribution of an anticancer drug is fundamental to reach an active concentration in neoplastic cells, ensuring the therapeutic effect. Determination of drug concentration in tumor homogenates by LC-MS/MS gives important information about this issue but the spatial inf...

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Detalles Bibliográficos
Autores principales: Morosi, Lavinia, Matteo, Cristina, Ceruti, Tommaso, Giordano, Silvia, Ponzo, Marianna, Frapolli, Roberta, Zucchetti, Massimo, Davoli, Enrico, D'Incalci, Maurizio, Ubezio, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7085221/
https://www.ncbi.nlm.nih.gov/pubmed/32210725
http://dx.doi.org/10.7150/ijbs.41395

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7085221/
https://www.ncbi.nlm.nih.gov/pubmed/32210725
http://dx.doi.org/10.7150/ijbs.41395

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