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MicroRNA-143 Increases Oxidative Stress and Myocardial Cell Apoptosis in a Mouse Model of Doxorubicin-Induced Cardiac Toxicity

BACKGROUND: Oxidative stress and myocardial apoptosis are features of doxorubicin-induced cardiac toxicity that can result in cardiac dysfunction. Previous studies showed that microRNA-143 (miR-143) was expressed in the myocardium and had a role in cardiac function. This study aimed to investigate t...

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Detalles Bibliográficos
Autores principales: Li, Xin-Qiang, Liu, Ya-Kui, Yi, Jun, Dong, Jia-Shou, Zhang, Pan-Pan, Wan, Lei, Li, Kui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7085239/
https://www.ncbi.nlm.nih.gov/pubmed/32170053
http://dx.doi.org/10.12659/MSM.920394