The in vitro anti-fibrotic effect of Pirfenidone on human pterygium fibroblasts is associated with down-regulation of autocrine TGF-β and MMP-1

We aimed to investigate the in vitro effect of pirfenidone (PFD) on proliferation, migration and collagen contraction of human pterygium fibroblasts (HPFs). HPFs were obtained from tissue explants during pterygium surgery. After treatment with pirfenidone, the HPFs proliferation was measured by MTT,...

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Detalles Bibliográficos
Autores principales: Tao, Yijin, Chen, Qin, Zhao, Can, Yang, Xiao, Cun, Qing, Yang, Wenyan, Zhang, Yuan, Zhu, Yingting, Zhong, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7085270/
https://www.ncbi.nlm.nih.gov/pubmed/32218695
http://dx.doi.org/10.7150/ijms.43238

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7085270/
https://www.ncbi.nlm.nih.gov/pubmed/32218695
http://dx.doi.org/10.7150/ijms.43238

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