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APOE4 moderates effects of cortical iron on synchronized default mode network activity in cognitively healthy old‐aged adults

INTRODUCTION: Apolipoprotein E ε4 (APOE4)–related genetic risk for sporadic Alzheimer's disease is associated with an early impairment of cognitive brain networks. The current study determines relationships between APOE4 carrier status, cortical iron, and cortical network‐functionality. METHODS...

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Detalles Bibliográficos
Autores principales: Kagerer, Sonja M., van Bergen, Jiri M. G., Li, Xu, Quevenco, Frances C., Gietl, Anton F., Studer, Sandro, Treyer, Valerie, Meyer, Rafael, Kaufmann, Philipp A., Nitsch, Roger M., van Zijl, Peter C. M., Hock, Christoph, Unschuld, Paul G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7085281/
https://www.ncbi.nlm.nih.gov/pubmed/32211498
http://dx.doi.org/10.1002/dad2.12002