Cargando…

APOE4 moderates effects of cortical iron on synchronized default mode network activity in cognitively healthy old‐aged adults

INTRODUCTION: Apolipoprotein E ε4 (APOE4)–related genetic risk for sporadic Alzheimer's disease is associated with an early impairment of cognitive brain networks. The current study determines relationships between APOE4 carrier status, cortical iron, and cortical network‐functionality. METHODS...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kagerer, Sonja M., van Bergen, Jiri M. G., Li, Xu, Quevenco, Frances C., Gietl, Anton F., Studer, Sandro, Treyer, Valerie, Meyer, Rafael, Kaufmann, Philipp A., Nitsch, Roger M., van Zijl, Peter C. M., Hock, Christoph, Unschuld, Paul G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Neuroimaging
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7085281/ https://www.ncbi.nlm.nih.gov/pubmed/32211498 http://dx.doi.org/10.1002/dad2.12002

Ejemplares similares

Functional Brain Network Connectivity Patterns Associated With Normal Cognition at Old-Age, Local β-amyloid, Tau, and APOE4
por: Quevenco, Frances C., et al.
Publicado: (2020)

Colocalization of cerebral iron with Amyloid beta in Mild Cognitive Impairment
por: van Bergen, J. M. G., et al.
Publicado: (2016)

Low Subicular Volume as an Indicator of Dementia-Risk Susceptibility in Old Age
por: Kagerer, Sonja M., et al.
Publicado: (2022)

Physical activity is associated with lower cerebral beta-amyloid and cognitive function benefits from lifetime experience–a study in exceptional aging
por: Treyer, Valerie, et al.
Publicado: (2021)

APOE ε4 and resting‐state functional connectivity in racially/ethnically diverse older adults
por: Turney, Indira C., et al.
Publicado: (2020)

Extracting default mode network based on graph neural network for resting state fMRI study
por: Wang, Donglin, et al.
Publicado: (2022)

Longitudinal association between hippocampus atrophy and episodic‐memory decline in non‐demented APOE ε4 carriers
por: Gorbach, Tetiana, et al.
Publicado: (2020)

Amnestic mild cognitive impairment individuals with dissimilar pathologic origins show common regional vulnerability in the default mode network
por: Rane, Swati, et al.
Publicado: (2018)

Symptomatic amyloid‐related imaging abnormalities in an APOE ε4/ε4 patient treated with aducanumab
por: VandeVrede, Lawren, et al.
Publicado: (2020)

Memory performance-related dynamic brain connectivity indicates pathological burden and genetic risk for Alzheimer’s disease
por: Quevenco, Frances C., et al.
Publicado: (2017)

Familiarity deficits in cognitively normal aging individuals with APOE ε4: A follow-up investigation of medial temporal lobe structural correlates
por: Schoemaker, Dorothee, et al.
Publicado: (2017)

GABA and glutamate moderate beta-amyloid related functional connectivity in cognitively unimpaired old-aged adults
por: Quevenco, F.C., et al.
Publicado: (2019)

Age-, sex-, and pathology-related variability in brain structure and cognition
por: Bachmann, Dario, et al.
Publicado: (2023)

Reduced uptake of [11C]‐ABP688, a PET tracer for metabolic glutamate receptor 5 in hippocampus and amygdala in Alzheimer’s dementia
por: Treyer, Valerie, et al.
Publicado: (2020)

A deep residual model for characterization of 5D spatiotemporal network dynamics reveals widespread spatiodynamic changes in schizophrenia
por: Kazemivash, Behnam, et al.
Publicado: (2023)

Added value of amyloid PET in individualized risk predictions for MCI patients
por: van Maurik, Ingrid S., et al.
Publicado: (2019)

Automatic measurements of fetal intracranial volume from 3D ultrasound scans
por: Caspi, Yaron, et al.
Publicado: (2022)

Nutritional status and structural brain changes in Alzheimer's disease: The NUDAD project
por: Verhaar, Barbara J.H., et al.
Publicado: (2020)

Lifestyle Affects Amyloid Burden and Cognition Differently in Men and Women
por: Bachmann, Dario, et al.
Publicado: (2022)

Lower cerebral blood flow in subjects with Alzheimer's dementia, mild cognitive impairment, and subjective cognitive decline using two-dimensional phase-contrast magnetic resonance imaging
por: Leijenaar, Jolien F., et al.
Publicado: (2017)

Small vessel disease lesion type and brain atrophy: The role of co‐occurring amyloid
por: Heinen, Rutger, et al.
Publicado: (2020)

Microbleeds are associated with depressive symptoms in Alzheimer's disease
por: Leeuwis, Anna E., et al.
Publicado: (2017)

A priori collaboration in population imaging: The Uniform Neuro-Imaging of Virchow-Robin Spaces Enlargement consortium
por: Adams, Hieab H.H., et al.
Publicado: (2015)

The effect of endovascular baroreflex amplification on central sympathetic nerve circuits and cerebral blood flow in patients with resistant hypertension: A functional MRI study
por: Groenland, Eline H., et al.
Publicado: (2022)

Value of repeated imaging in patients with a stroke who are transferred for endovascular treatment
por: van Meenen, Laura C C, et al.
Publicado: (2022)

Quantification of subcortical gray-matter vascularization using 7 Tesla time-of-flight angiography
por: Laurig, Mathias, et al.
Publicado: (2013)

Cortical Amyloid Beta in Cognitively Normal Elderly Adults is Associated with Decreased Network Efficiency within the Cerebro-Cerebellar System
por: Steininger, Stefanie C., et al.
Publicado: (2014)

Frameless multimodal image guidance of localized convection-enhanced delivery of therapeutics in the brain
por: van der Bom, Imramsjah M J, et al.
Publicado: (2013)

White matter microstructure disruption in early stage amyloid pathology
por: Collij, Lyduine E., et al.
Publicado: (2021)

Regional amyloid accumulation predicts memory decline in initially cognitively unimpaired individuals
por: Collij, Lyduine E., et al.
Publicado: (2021)

Thinner temporal and parietal cortex is related to incident clinical progression to dementia in patients with subjective cognitive decline
por: Verfaillie, Sander C.J., et al.
Publicado: (2016)

Clinical use of amyloid-positron emission tomography neuroimaging: Practical and bioethical considerations
por: Witte, Michael M., et al.
Publicado: (2015)

The butterfly effect: improving brain cone-beam CT image artifacts for stroke assessment using a novel dual-axis trajectory
por: Cancelliere, Nicole Mariantonia, et al.
Publicado: (2023)

Critical review of the Appropriate Use Criteria for amyloid imaging: Effect on diagnosis and patient care
por: Apostolova, Liana G., et al.
Publicado: (2016)

White matter changes in empirically derived incident MCI subtypes in the Mayo Clinic Study of Aging
por: Machulda, Mary M., et al.
Publicado: (2021)

Multiplex core of the human brain using structural, functional and metabolic connectivity derived from hybrid PET-MR imaging
por: Devrome, Martijn, et al.
Publicado: (2023)

Test-Retest Reliability of fMRI During an Emotion Processing Task: Investigating the Impact of Analytical Approaches on ICC Values
por: Heilicher, Mickela, et al.
Publicado: (2022)

Intracranial arterial four-dimensional flow is associated with metrics of brain health and Alzheimer's disease
por: Berman, Sara E., et al.
Publicado: (2015)

High blood pressure predicts hippocampal atrophy rate in cognitively impaired elders
por: Fiford, Cassidy M., et al.
Publicado: (2020)

Decoding the Brain's Surface to Track Deeper Activity
por: Tenzer, Mark L., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_ro7s27o2oq6fapo62bq66fgip8