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Amyloid duration is associated with preclinical cognitive decline and tau PET

INTRODUCTION: This study applies a novel algorithm to longitudinal amyloid positron emission tomography (PET) imaging to identify age‐heterogeneous amyloid trajectory groups, estimate the age and duration (chronicity) of amyloid positivity, and investigate chronicity in relation to cognitive decline...

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Detalles Bibliográficos
Autores principales: Koscik, Rebecca L., Betthauser, Tobey J., Jonaitis, Erin M., Allison, Samantha L., Clark, Lindsay R., Hermann, Bruce P., Cody, Karly A., Engle, Jonathan W., Barnhart, Todd E., Stone, Charles K., Chin, Nathaniel A., Carlsson, Cynthia M., Asthana, Sanjay, Christian, Bradley T., Johnson, Sterling C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7085284/
https://www.ncbi.nlm.nih.gov/pubmed/32211502
http://dx.doi.org/10.1002/dad2.12007