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MR1 displays the microbial metabolome driving selective MR1-restricted T cell receptor usage

MR1-restricted T cells (MR1Ts) are a T cell subset that recognize and mediate host defense to a broad array of microbial pathogens, including respiratory pathogens (e.g., Mycobacterium tuberculosis, Streptococcus pyogenes, and Francisella tularensis) and enteric pathogens (e.g., Escherichia coli and...

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Detalles Bibliográficos
Autores principales: Harriff, Melanie J., McMurtrey, Curtis, Froyd, Cara A., Jin, Haihong, Cansler, Meghan, Null, Megan, Worley, Aneta, Meermeier, Erin W., Swarbrick, Gwendolyn, Nilsen, Aaron, Lewinsohn, Deborah A., Hildebrand, William, Adams, Erin J., Lewinsohn, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7085347/
https://www.ncbi.nlm.nih.gov/pubmed/30006464
http://dx.doi.org/10.1126/sciimmunol.aao2556