Development and Validation of LC-MS/MS for Analyzing Potential Genotoxic Impurities in Pantoprazole Starting Materials

Pantoprazole sodium (PPZS) is a selective proton pump inhibitor used in the prevention and treatment of gastric acid-related diseases. Six potentially genotoxic impurities (PGIs) are involved in 5-difluoromethoxy-2-mercapto-1H-benzimidazole (DMBZ), which is the starting material of PPZS. To date, no...

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Detalles Bibliográficos
Autores principales: Chen, Yuyuan, Wu, Song, Yang, Qingyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7085375/
https://www.ncbi.nlm.nih.gov/pubmed/32211210
http://dx.doi.org/10.1155/2020/6597363

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7085375/
https://www.ncbi.nlm.nih.gov/pubmed/32211210
http://dx.doi.org/10.1155/2020/6597363

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