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The Molecular Basis of the Interaction of Cyclophilin A with α‐Synuclein
Peptidylprolyl isomerases (PPIases) catalyze cis/trans isomerization of prolines. The PPIase CypA colocalizes with the Parkinson's disease (PD)‐associated protein α‐synuclein in cells and interacts with α‐synuclein oligomers. Herein, we describe atomic insights into the molecular details of the...
Autores principales: | Favretto, Filippo, Baker, Jeremy D., Strohäker, Timo, Andreas, Loren B., Blair, Laura J., Becker, Stefan, Zweckstetter, Markus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7085457/ https://www.ncbi.nlm.nih.gov/pubmed/31830361 http://dx.doi.org/10.1002/anie.201914878 |
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