Cargando…

Cytokeratin 5 alters β-catenin dynamics in breast cancer cells

Estrogen receptor (ER) positive breast cancers often contain subpopulations of cells that express the intermediate filament protein cytokeratin 5 (CK5). CK5+ cells are enriched in cancer stem cell (CSC) properties, can be induced by progestins, and predict poor prognosis in ER+ breast cancer. We est...

Descripción completa

Detalles Bibliográficos
Autores principales: McGinn, Olivia, Ward, Ashley V., Fettig, Lynsey M., Riley, Duncan, Ivie, Joshua, Paul, Kiran V., Kabos, Peter, Finlay-Schultz, Jessica, Sartorius, Carol A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7085458/
https://www.ncbi.nlm.nih.gov/pubmed/31988452
http://dx.doi.org/10.1038/s41388-020-1164-0