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Pre‐existing heterologous T‐cell immunity and neoantigen immunogenicity

Neoantigens are tumor‐specific mutated proteins that are exempt from central tolerance and are therefore capable of efficiently eliciting effective T‐cell responses. The identification of immunogenic neoantigens in tumor‐specific mutated proteins has promising clinical implications for cancer immuno...

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Detalles Bibliográficos
Autores principales: Leng, Qibin, Tarbe, Marion, Long, Qi, Wang, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7085466/
https://www.ncbi.nlm.nih.gov/pubmed/32211191
http://dx.doi.org/10.1002/cti2.1111