Restoration of MARCK enhances chemosensitivity in cancer

PURPOSE: Increased ATP-binding-cassette (ABC) transporter activity is a major cause of chemotherapy resistance in cancer. The ABC transporter family member ABCB1 is often overexpressed in colorectal cancer (CRC). Phosphatidylinositol-4,5-bisphosphat (PI(4,5)P(2))-dependent pathways are involved in t...

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Detalles Bibliográficos
Autores principales: Wenzel, Tim, Büch, Thomas, Urban, Nicole, Weirauch, Ulrike, Schierle, Katrin, Aigner, Achim, Schaefer, Michael, Kalwa, Hermann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Original Article – Cancer Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7085482/
https://www.ncbi.nlm.nih.gov/pubmed/32056006
http://dx.doi.org/10.1007/s00432-020-03149-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7085482/
https://www.ncbi.nlm.nih.gov/pubmed/32056006
http://dx.doi.org/10.1007/s00432-020-03149-2

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