Osmotic and hypoxic induction of osteopontin in retinal pigment epithelial cells: Involvement of purinergic receptor signaling

PURPOSE: Osteopontin (OPN) is a neuroprotective factor in the retina that improves photoreceptor survival. The aim of the present study was to investigate whether human RPE cells express and respond to OPN. METHODS: Hypoxia and chemical hypoxia were induced by cell culture in 0.25% O(2) and the addi...

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Detalles Bibliográficos
Autores principales: Hollborn, Margrit, Brück, Ricarda, Kuhrt, Heidrun, Wiedemann, Peter, Bringmann, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086046/
https://www.ncbi.nlm.nih.gov/pubmed/32214785

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086046/
https://www.ncbi.nlm.nih.gov/pubmed/32214785

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