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Osmotic and hypoxic induction of osteopontin in retinal pigment epithelial cells: Involvement of purinergic receptor signaling

PURPOSE: Osteopontin (OPN) is a neuroprotective factor in the retina that improves photoreceptor survival. The aim of the present study was to investigate whether human RPE cells express and respond to OPN. METHODS: Hypoxia and chemical hypoxia were induced by cell culture in 0.25% O(2) and the addi...

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Detalles Bibliográficos
Autores principales:	Hollborn, Margrit, Brück, Ricarda, Kuhrt, Heidrun, Wiedemann, Peter, Bringmann, Andreas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Molecular Vision 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086046/ https://www.ncbi.nlm.nih.gov/pubmed/32214785

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