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A Depletion of Stop Codons in lincRNA is Owing to Transfer of Selective Constraint from Coding Sequences

Although the constraints on a gene’s sequence are often assumed to reflect the functioning of that gene, here we propose transfer selection, a constraint operating on one class of genes transferred to another, mediated by shared binding factors. We show that such transfer can explain an otherwise pa...

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Detalles Bibliográficos
Autores principales: Abrahams, Liam, Hurst, Laurence D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086181/
https://www.ncbi.nlm.nih.gov/pubmed/31841162
http://dx.doi.org/10.1093/molbev/msz299