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miR-4458 directly targets IGF1R to inhibit cell proliferation and promote apoptosis in hemangioma

Hemangiomas (HAs) are benign neoplasms of the vasculature. MicroRNA-4458 (miR-4458) has been reported to function as a tumor suppressor in multiple malignancies, but its biological function in HAs remains unknown. In the present study, the potential role of miR-4458 in HA-derived endothelial cells (...

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Detalles Bibliográficos
Autores principales: Wu, Maosong, Tang, Yongsheng, Hu, Gang, Yang, Chunjian, Ye, Kaichuang, Liu, Xianluo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086214/
https://www.ncbi.nlm.nih.gov/pubmed/32256788
http://dx.doi.org/10.3892/etm.2020.8546