Effects of mevalonate kinase interference on cell differentiation, apoptosis, prenylation and geranylgeranylation of human keratinocytes are attenuated by farnesyl pyrophosphate or geranylgeranyl pyrophosphate

Mevalonate kinase (MVK) mutations were previously identified in disseminated superficial actinic porokeratosis. However, the role of MVK in differentiation, apoptosis and prenylation of keratinocytes requires further investigation. Farnesyl pyrophosphate (FPP) and geranylgeranyl pyrophosphate (GGPP)...

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Detalles Bibliográficos
Autores principales: Li, Min, Min, Wei, Wang, Jianbo, Wang, Lu, Li, Yan, Zhou, Naihui, Yang, Ziliang, Qian, Qihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086283/
https://www.ncbi.nlm.nih.gov/pubmed/32256770
http://dx.doi.org/10.3892/etm.2020.8569

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086283/
https://www.ncbi.nlm.nih.gov/pubmed/32256770
http://dx.doi.org/10.3892/etm.2020.8569

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