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TERT, a promoter of CNS malignancies

As cells replicate their DNA during mitosis, telomeres are shortened due to the inherent limitations of the DNA replication process. Maintenance of telomere length is critical for cancer cells to overcome cellular senescence induced by telomere shortening. Telomerase reverse transcriptase (TERT) is...

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Detalles Bibliográficos
Autores principales: Patel, Bhuvic, Taiwo, Rukayat, Kim, Albert H, Dunn, Gavin P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086299/
https://www.ncbi.nlm.nih.gov/pubmed/32226942
http://dx.doi.org/10.1093/noajnl/vdaa025