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A miR-146a-5p/TRAF6/NF-kB p65 axis regulates pancreatic cancer chemoresistance: functional validation and clinical significance

Background: Dysregulated microRNA (miRNA) expression in cancer can act as a key factor that modifies biological processes, including chemoresistance. Our study aimed to identify the miRNAs associated with gemcitabine (GEM) resistance in pancreatic ductal adenocarcinoma (PDAC) and to explore the pote...

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Detalles Bibliográficos
Autores principales: Meng, Qingcai, Liang, Chen, Hua, Jie, Zhang, Bo, Liu, Jiang, Zhang, Yiyin, Wei, Miaoyan, Yu, Xianjun, Xu, Jin, Shi, Si
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086345/
https://www.ncbi.nlm.nih.gov/pubmed/32226532
http://dx.doi.org/10.7150/thno.40566