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Serelaxin alleviates cardiac fibrosis through inhibiting endothelial-to-mesenchymal transition via RXFP1

Rationale: Cardiac fibrosis is an integral constituent of every form of chronic heart disease, and persistence of fibrosis reduces tissue compliance and accelerates the progression to heart failure. Relaxin-2 is a human hormone, which has various physiological functions such as mediating renal vasod...

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Detalles Bibliográficos
Autores principales: Wilhelmi, Tim, Xu, Xingbo, Tan, Xiaoying, Hulshoff, Melanie S., Maamari, Sabine, Sossalla, Samuel, Zeisberg, Michael, Zeisberg, Elisabeth M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086357/
https://www.ncbi.nlm.nih.gov/pubmed/32226528
http://dx.doi.org/10.7150/thno.38640