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Serelaxin alleviates cardiac fibrosis through inhibiting endothelial-to-mesenchymal transition via RXFP1
Rationale: Cardiac fibrosis is an integral constituent of every form of chronic heart disease, and persistence of fibrosis reduces tissue compliance and accelerates the progression to heart failure. Relaxin-2 is a human hormone, which has various physiological functions such as mediating renal vasod...
Autores principales: | Wilhelmi, Tim, Xu, Xingbo, Tan, Xiaoying, Hulshoff, Melanie S., Maamari, Sabine, Sossalla, Samuel, Zeisberg, Michael, Zeisberg, Elisabeth M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086357/ https://www.ncbi.nlm.nih.gov/pubmed/32226528 http://dx.doi.org/10.7150/thno.38640 |
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