Effective targeting of intact and proteolysed CDCP1 for imaging and treatment of pancreatic ductal adenocarcinoma

Background: CUB domain-containing protein 1 (CDCP1) is a cell surface receptor regulating key signalling pathways in malignant cells. CDCP1 has been proposed as a molecular target to abrogate oncogenic signalling pathways and specifically deliver anti-cancer agents to tumors. However, the developmen...

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Detalles Bibliográficos
Autores principales: Kryza, Thomas, Khan, Tashbib, Puttick, Simon, Li, Chao, Sokolowski, Kamil A, Tse, Brian WC, Cuda, Tahleesa, Lyons, Nicholas, Gough, Madeline, Yin, Julia, Parkin, Ashleigh, Deryugina, Elena I, Quigley, James P., Law, Ruby H. P., Whisstock, James C., Riddell, Andrew D., Barbour, Andrew P., Wyld, David K., Thomas, Paul A., Rose, Stephen, Snell, Cameron E., Pajic, Marina, He, Yaowu, Hooper, John D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086361/
https://www.ncbi.nlm.nih.gov/pubmed/32226543
http://dx.doi.org/10.7150/thno.43589

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086361/
https://www.ncbi.nlm.nih.gov/pubmed/32226543
http://dx.doi.org/10.7150/thno.43589

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