Loss of EGR-1 uncouples compensatory responses of pancreatic β cells

Rationale: Subjects unable to sustain β-cell compensation develop type 2 diabetes. Early growth response-1 protein (EGR-1), implicated in the regulation of cell differentiation, proliferation, and apoptosis, is induced by diverse metabolic challenges, such as glucose or other nutrients. Therefore, w...

Descripción completa

Detalles Bibliográficos
Autores principales: Leu, Sy-Ying, Kuo, Li-Hua, Weng, Wen-Tsan, Lien, I-Chia, Yang, Ching-Chun, Hsieh, Tai-Tzu, Cheng, Yi-Ning, Chien, Po-Hsiu, Ho, Li-Chun, Chen, Shun-Hua, Shan, Yan-Shen, Chen, Yun-Wen, Tsai, Pei-Jane, Sung, Junne-Ming, Tsai, Yau-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086362/
https://www.ncbi.nlm.nih.gov/pubmed/32226550
http://dx.doi.org/10.7150/thno.40664

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086362/
https://www.ncbi.nlm.nih.gov/pubmed/32226550
http://dx.doi.org/10.7150/thno.40664

Ejemplares similares