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Loss of EGR-1 uncouples compensatory responses of pancreatic β cells

Rationale: Subjects unable to sustain β-cell compensation develop type 2 diabetes. Early growth response-1 protein (EGR-1), implicated in the regulation of cell differentiation, proliferation, and apoptosis, is induced by diverse metabolic challenges, such as glucose or other nutrients. Therefore, w...

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Detalles Bibliográficos
Autores principales:	Leu, Sy-Ying, Kuo, Li-Hua, Weng, Wen-Tsan, Lien, I-Chia, Yang, Ching-Chun, Hsieh, Tai-Tzu, Cheng, Yi-Ning, Chien, Po-Hsiu, Ho, Li-Chun, Chen, Shun-Hua, Shan, Yan-Shen, Chen, Yun-Wen, Tsai, Pei-Jane, Sung, Junne-Ming, Tsai, Yau-Sheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086362/ https://www.ncbi.nlm.nih.gov/pubmed/32226550 http://dx.doi.org/10.7150/thno.40664

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