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JNK suppresses melanogenesis by interfering with CREB-regulated transcription coactivator 3-dependent MITF expression

Melanogenesis is a critical self-defense mechanism against ultraviolet radiation (UVR)-induced skin damage and carcinogenesis; however, dysregulation of melanin production and distribution causes skin-disfiguring pigmentary disorders. Melanogenesis is initiated by UVR-induced cAMP generation and ens...

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Detalles Bibliográficos
Autores principales: Kim, Ji-Hye, Hong, A-reum, Kim, Yo-Han, Yoo, Hanju, Kang, Sang-Wook, Chang, Sung Eun, Song, Youngsup
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086364/
https://www.ncbi.nlm.nih.gov/pubmed/32226536
http://dx.doi.org/10.7150/thno.41502