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JNK suppresses melanogenesis by interfering with CREB-regulated transcription coactivator 3-dependent MITF expression
Melanogenesis is a critical self-defense mechanism against ultraviolet radiation (UVR)-induced skin damage and carcinogenesis; however, dysregulation of melanin production and distribution causes skin-disfiguring pigmentary disorders. Melanogenesis is initiated by UVR-induced cAMP generation and ens...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086364/ https://www.ncbi.nlm.nih.gov/pubmed/32226536 http://dx.doi.org/10.7150/thno.41502 |