Total Chemical Synthesis of ISGylated-Ubiquitin Hybrid Chain Assisted by Acetamidomethyl Derivatives with Dual Functions

[Image: see text] Interferon-stimulated gene 15 (ISG15) is a member of the ubiquitin-like modifiers (ULM) family, which adopts a β-grasp fold domain(s) similar to ubiquitin (Ub) with only minor sequence homology. ISG15 consists of two Ub-like domains and aids the immune system in neutralizing infect...

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Detalles Bibliográficos
Autores principales: Eid, Emad, Boross, Gábor N., Sun, Hao, Msallam, Muna, Singh, Sumeet K., Brik, Ashraf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086396/
https://www.ncbi.nlm.nih.gov/pubmed/32069038
http://dx.doi.org/10.1021/acs.bioconjchem.0c00026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086396/
https://www.ncbi.nlm.nih.gov/pubmed/32069038
http://dx.doi.org/10.1021/acs.bioconjchem.0c00026

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