C–N Coupling of DNA-Conjugated (Hetero)aryl Bromides and Chlorides for DNA-Encoded Chemical Library Synthesis

[Image: see text] DNA-encoded chemical library (DECL) screens are a rapid and economical tool to identify chemical starting points for drug discovery. As a robust transformation for drug discovery, palladium-catalyzed C–N coupling is a valuable synthetic method for the construction of DECL chemical...

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Detalles Bibliográficos
Autores principales: Chen, Ying-Chu, Faver, John C., Ku, Angela F., Miklossy, Gabriella, Riehle, Kevin, Bohren, Kurt M., Ucisik, Melek N., Matzuk, Martin M., Yu, Zhifeng, Simmons, Nicholas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086399/
https://www.ncbi.nlm.nih.gov/pubmed/32019312
http://dx.doi.org/10.1021/acs.bioconjchem.9b00863

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086399/
https://www.ncbi.nlm.nih.gov/pubmed/32019312
http://dx.doi.org/10.1021/acs.bioconjchem.9b00863

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