Poor Concordance of Floxed Sequence Recombination in Single Neural Stem Cells: Implications for Cell Autonomous Studies

To manipulate target gene function in specific adult cell populations, tamoxifen (TAM)-dependent CreER(T2) is widely used to drive inducible, site-specific recombination of loxP flanked sequences. In studies of cell autonomous target gene function, it is common practice to combine these CreER(T2)-lo...

Descripción completa

Detalles Bibliográficos
Autores principales: Dause, Tyler Joseph, Kirby, Elizabeth Diana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2020
Materias:
Research Article: Theory/New Concepts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086402/
https://www.ncbi.nlm.nih.gov/pubmed/32079584
http://dx.doi.org/10.1523/ENEURO.0470-19.2020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086402/
https://www.ncbi.nlm.nih.gov/pubmed/32079584
http://dx.doi.org/10.1523/ENEURO.0470-19.2020

Ejemplares similares