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Poor Concordance of Floxed Sequence Recombination in Single Neural Stem Cells: Implications for Cell Autonomous Studies

To manipulate target gene function in specific adult cell populations, tamoxifen (TAM)-dependent CreER(T2) is widely used to drive inducible, site-specific recombination of loxP flanked sequences. In studies of cell autonomous target gene function, it is common practice to combine these CreER(T2)-lo...

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Detalles Bibliográficos
Autores principales:	Dause, Tyler Joseph, Kirby, Elizabeth Diana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Society for Neuroscience 2020
Materias:	Research Article: Theory/New Concepts
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086402/ https://www.ncbi.nlm.nih.gov/pubmed/32079584 http://dx.doi.org/10.1523/ENEURO.0470-19.2020

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