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Chidamide Inhibits Glioma Cells by Increasing Oxidative Stress via the miRNA-338-5p Regulation of Hedgehog Signaling

OBJECTIVE: Chidamide has a broad spectrum of antitumor activity but its function on glioma remains unknown. The increase of reactive oxygen species (ROS) and reactive nitrogen species (RNS) may control glioma risk by promoting its apoptosis and necrosis. Hedgehog pathway is crucial to glioma cell pr...

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Detalles Bibliográficos
Autores principales: Zhou, Haixia, Han, Liang, Wang, Han, Wei, Jun, Guo, Zhigang, Li, Zhaohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086450/
https://www.ncbi.nlm.nih.gov/pubmed/32256960
http://dx.doi.org/10.1155/2020/7126976