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Primary demyelination in experimental canine distemper virus induced encephalomyelitis in gnotobiotic dogs: Sequential immunologic and morphologic findings

Experimental infection of gnotobiotic Beagle dogs at 21 days of age with neurovirulent R252 strain of canine distemper virus (R252-CDV) resulted in a non-suppurative encephalomyelitis. Segmental internodal primary demyelination was found in almost 90% of the dogs from 27 days post inoculation (DPI)....

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Detalles Bibliográficos
Autores principales: Higgins, R. J., Krakowka, S. G., Metzler, A. E., Koestner, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 1982
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086558/
https://www.ncbi.nlm.nih.gov/pubmed/7136512
http://dx.doi.org/10.1007/BF00692691