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Identification of amino acids in highly pathogenic avian influenza H5N1 virus hemagglutinin that determine avian influenza species specificity

To test the role of neutralizing antibodies (nAbs) and receptor adaptation in interspecies transmission of influenza virus, two H5N1 strains, isolated from human and avian hosts, with four amino acid differences in hemagglutinin (HA) and seven HA mutations were studied. We found that a mutation at a...

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Detalles Bibliográficos
Autores principales: Li, Zheng, Liu, Zhonghua, Ma, Chi, Zhang, Linqi, Su, Yuelong, Gao, George F., Li, Zi, Cui, Lianxian, He, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086585/
https://www.ncbi.nlm.nih.gov/pubmed/21744000
http://dx.doi.org/10.1007/s00705-011-1056-2